منابع مشابه
Lens superoxide dismutase and catalase activities in diabetic cataract.
OBJECTIVE Biochemical evidence suggests that the oxidative damage of the lens proteins is involved in the genesis of senile cataract and the development of diabetes-related pathologic changes such as the formation of cataracts. In particular, lens proteins are subject to extensive oxidative modification. Oxidative damage either decreases the antioxidant capacity or decreased antioxidant capacit...
متن کاملDiabetic cataract formation: potential role of glycosylation of lens crystallins.
A high glucose concentration in vivo or an increased glucose of glucose 6-phosphate concentration in vitro has been found to lead to the glycosylation of epsilon-amino groups of lysine residues in bovine and rat lens crystallins. In vitro, this glycosylation imparts an increased susceptibility of the crystallins to sulfhydryl oxidation. Disulfide crosslinks result in the formation of high molec...
متن کامل2347 Diabetic cataract and oxidative degradation of lens proteins
Purpose: Lipid peroxidation has recently been associated to a number of agcrelated diseases including cataract development. This study was designed to establish the best conditions to adapt a technical approach based on the incorporation of a fluorescent pmbe (patina& acid) into biological membranes to monitor early stages of lipid pemxidation. The method allows both the evaluation of several f...
متن کاملLipid peroxides level in the Indonesian elderly
A cross-sectional study was done to see the possible association of plasma lipid peroxides in the elderly with age and other factors. Plasma lipid peroxides is a product of free radical reactions which according to the latest theory of aging is the cause of aging process. Lipid peroxides were also found high in coronary heart disease. Four hundred forty relatively healthy elderly, age 55-85 yea...
متن کاملLens thickness in early cataract.
The search for environmental factors associated with cataract has produced conflicting evidence and one possible reason may be that environmental influences are initiating events occurring perhaps for short periods many years before loss of sight from cataract. It is important, therefore, to be able to detect the earliest changes of cataract formation so that epidemiological studies have a bett...
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ژورنال
عنوان ژورنال: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
سال: 1997
ISSN: 0004-5632,1758-1001
DOI: 10.1177/000456329703400620